Research Associate II - Immuno-Oncology

City of Hope

Duarte, CA

Job posting number: #7102445 (Ref:10014217)

Posted: August 5, 2022

Application Deadline: Open Until Filled

Job Description

About City of Hope

City of Hope is an independent biomedical research and treatment organization for cancer, diabetes and other life-threatening diseases.

Founded in 1913, City of Hope is a leader in bone marrow transplantation and immunotherapy such as CAR T cell therapy. City of Hope’s translational research and personalized treatment protocols advance care throughout the world. Human synthetic insulin, monoclonal antibodies and numerous breakthrough cancer drugs are based on technology developed at the institution.  AccessHope™, a subsidiary launched in 2019 serves employers and their health care partners by providing access to City of Hope’s specialized cancer expertise.

A National Cancer Institute-designated comprehensive cancer center and a founding member of the National Comprehensive Cancer Network, City of Hope is ranked among the nation’s “Best Hospitals” in cancer by U.S. News & World Report and received Magnet Recognition from the American Nurses Credentialing Center. Its main campus is located near Los Angeles, with additional locations throughout Southern California and in Arizona.

City of Hope’s commitment to Diversity, Equity and Inclusion

We believe diversity, equity and inclusion is key in serving our mission to provide compassionate patient care, drive innovative discovery, and advance vital education focused on eliminating cancer and diabetes in all of our communities.  Our commitment to Diversity, Equity and Inclusion ensures we bring the full range of skills, perspectives, cultural backgrounds and experiences to our work -- and that our teams align with the people we serve in order to build trust and understanding.  We are dedicated to fostering a community that embraces diversity - in ideas, backgrounds and perspectives; this is reflected in our work and represented in our people.

Position Summary

Our group in the Immuno-Oncology Department in the Beckman Research Institute at the City of Hope is interested in developing prophylactic and therapeutic strategic against oncogenic herpesviruses and their associated malignancies, with the ultimate goal of translating these strategies into the clinic. We are currently preparing one of our vaccine candidates for clinical translation. We are looking for a highly motivated individual with previous experience in Good Laboratory Practice (GLP) or Good Manufacturing Practice (GMP) environments to help us achieve our goal. Additionally, this individual will oversee general laboratory maintenance, generation of critical reagents (protein and antibodies), and will also be involved in additional pre-clinical animal studies.

Key Responsibilities include:

  • Managing essential day-to-day laboratory operations (i.e. lab supply/reagent purchasing, equipment/instrument maintenance) under the supervision of the PI
  • Performing experiments under GLP/GMP conditions, and writing and maintaining the associated GLP/GMP standard operating procedures (SOPs) and reports
  • Cell culture including application of aseptic techniques for media compounding, passaging, maintenance and cryopreservation of cell cultures
  • Protein/antibody production in mammalian cell systems, and purification (ÄKTA pure system)
  • Mouse handling (injections, collection of blood and tissues)

Basic education, experience and skills required for consideration:

  • Bachelor’s degree. Masters degree preferred.
  • Two years related research/ laboratory experience with a Bachelor’s degree or
  • One year related research/ laboratory experience with a Master’s degree
  • Excellent verbal and written communication skills.
  • Excellent interpersonal skills.

Preferred education, experience and skills:

  • Previous experience on GLP/GMP environment, and writing/maintenance of SOPs
  • Extensive hands-on experience in cell culture and aseptic technique
  • Previous experience in protein production and purification in mammalian cell systems

Additional Information:

For more information on Dr. Javier Ogembo’s Research, please visit here.

As a condition of employment, City of Hope requires staff to comply with all state and federal vaccination mandates.

City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer.  All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.

City of Hope is a community of people characterized by our diversity of thought, background and approach, but tied together by our commitment to care for and cure those with cancer and other life-threatening diseases. The innovation that our diversity produces in the areas of research, treatment, philanthropy and education has made us national leaders in this fight. Our unique and diverse workforce provides us the ability to understand our patients' needs, deliver compassionate care and continue the quest for a cure for life-threatening diseases. At City of Hope, diversity and inclusion is a core value at the heart of our mission. We strive to create an inclusive workplace environment that engages all of our employees and provides them with opportunities to develop and grow, both personally and professionally. Each day brings an opportunity to strengthen our work, leverage our different perspectives and improve our patients’ experiences by learning from others. Diversity and inclusion is about much more than policies and campaigns. It is an integral part of who we are as an institution, how we operate and how we see our future.

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