Diagnostic & GQC Technologist
Job posting number: #7099602 (Ref:JR001865)
Posted: May 9, 2022
Application Deadline: Open Until Filled
The Diagnostic Laboratory at The Jackson Laboratory assures the health and well-being of our mouse colonies by routine health monitoring for undesirable infectious agents. Our diagnostic program serves to monitor against potential disease outbreaks in the Production, Research, and Repository colonies, as well as verifying the health status of foster mothers used for rederivation of mouse strains by Reproductive Sciences. The Diagnostic Laboratory also performs environmental monitoring via microbiologic culture of mouse room swabs. This testing strategy includes necropsy, serology, microbiology, and parasitology. The Genetic Quality Control (GQC) Laboratory at The Jackson Laboratory serves to detect and eliminate contamination in the genetic background of all of our Production and Repository colonies by routine and investigative screening using a panel of molecular assays.
This role involves the following 5 testing areas and Technologists may be assigned to any of the areas:
Complete necropsy involves the visual observation of all the organs, a description of any lesions seen, and the use of proper necropsy procedures. Selection of abnormal tissues for testing or histopathology. Use of aseptic techniques for the procurement of tissue samples for microbiological testing, for molecular testing, and for parasitology. Obtain blood samples from caudal venous and arterial sites or cardiac puncture for serological evaluation.
Perform parasitological examinations for ectoparasites with the use of a dissecting stereoscope. Parasitological examinations for endoparasites are done visually and microscopically. Further, perform specialized testing (fecal floatations, tape tests, etc) as required.
Performance of Luminex, ELISA and IFA procedures. This involves dilution of samples, preparation of reagents, performance of the assay, operation and maintenance of sophisticated instrumentation, and interpretation of results.
Preparation and quality control of microbiological media and chemical solutions. Further, this involves performance of subcultures, setting up biochemical identification testing for microbes, operation and maintenance of sophisticated instrumentation, and performance of other microbiological assays as required.
Digestion of routine tissue samples for extraction/purification of DNA when applicable, and coordination of outsourcing SNP assays for the purpose of monitoring genetic background. May be required to perform molecular assays in house.
- Bachelor’s degree in Biological Sciences, or closely related discipline as required. Other means of acquiring this knowledge may be evaluated on a case-by-case basis.
- 0-2 years of experience working in a laboratory setting is required.
- Problem-solving skills and attention to detail, organize time effectively and the ability to learn new techniques in a timely manner.
- Proficiency in using computer software and possesses database skills in Word, Excel, Outlook, etc. and all other appropriate software used in Jackson Laboratory operations (such as Sample Tracker and the TGS Database).
- Strong communication skills sufficient to permit clear and effective exchange of information with people representing a wide diversity of disciplines and levels of sophistication.
- Ability to contribute positively to the team by putting in extra effort and demonstrating the ability to work in a fast paced, change and technology driven, diverse work group.
- Experience in identifying microorganisms using phenotypic and/or molecular techniques.
Please submit a cover letter of interest and resume!
The Jackson Laboratory (JAX) is an independent, nonprofit biomedical research institution with more than 2,400 employees. Headquartered in Bar Harbor, Maine, it has a National Cancer Institute-designated Cancer Center in Augusta, Maine, a genomic medicine institute in Farmington, Connecticut, and facilities in Ellsworth, Maine, Sacramento, California, and Shanghai, China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.
JAX employees work in a collaborative, value-driven, and team-based environment where the focus is on advancing science and improving patients’ lives. Researchers apply genetics to increase the understanding of human disease and advance treatments and cures for cancer, neurological and immune disorders, diabetes, aging, and heart disease. JAX was voted among the top 15 “Best Places to Work in Academia” in the United States in a poll conducted by The Scientist magazine!
The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.