Job posting number: #7081754
Posted: August 2, 2021
Application Deadline: Open Until Filled
Job DescriptionDepartment Information
The Herman B Wells Center for Pediatric Research conducts basic science and translational research within the Department of Pediatrics at Indiana University School of Medicine. The Wells Center houses more than 200 faculty investigators, staff, and trainees seeking answers to the most pressing questions related to childhood illness.
With the collaboration between scientists and physicians, the center aims to increase knowledge of causes and mechanisms of serious pediatric diseases. Our goal is to develop innovative approaches to the diagnosis and treatment of sick children in Indiana and beyond.
A position is open for a full-time Research Technician in the Herman B Wells Center for Pediatric Research in the laboratory of Steven Rhodes, MD, PhD. The Rhodes lab focuses on using genetically engineered mouse models and patient samples coupled with single cell and multiomic approaches to dissect the biology of malignant peripheral nerve sheath tumors and their precursors in the neurofibromatosis type 1 (NF1) cancer predisposition syndrome. The technician will conduct experiments pertinent to cancer biology and immuno-oncology including protein biochemistry, shRNA/CRISPR gene editing, gene expression analysis (using bulk and single cell next generation sequencing assays), FACS analysis, drug screens, cell culture and animal studies. The Rhodes lab is seeking to combine talented individuals with state-of-the-art technologies to serve patients with NF1 by advancing novel therapies to the clinic while training the next generation of physicians and researchers.
Primary Responsibilities Include:
Design and conduct a variety of experiments using both in vitro, in vivo rodent models and patient samples
Development and optimization of standard operating procedures for the lab
Set up, maintain and troubleshoot equipment
Order and maintain laboratory supplies
Maintain a detailed laboratory notebook of all lab-related activities
Record, analyze, interpret, summarize/organize and present experimental data
Participate in grant writing and manuscript preparation
Performs a wide variety of complex experiments and reports results
Keeps organized analytical data of performed experiments
Provides support for equipment maintenance as needed
Acts as a liaison to students and laboratory personnel for training
Maintains laboratory supply requisition and management
May train junior-level staff.
May help plan experiments or short-term goals.
Bachelor's degree in science or a related field
Prior laboratory experience in at least some of the experimental methodologies described above, particularly in the area of molecular biology. Additional techniques will be taught.
Proficient communication skills
Maintains a high degree of professionalism
Demonstrated time management and priority setting skills
Demonstrates a high commitment to quality
Possesses flexibility to work in a fast paced, dynamic environment
Highly thorough and dependable
Punctual, hardworking, and well organized with excellent time management and goal setting skill
Ability to work both independently and collaboratively as a team member
Maintain a high degree of professionalism and integrity
Enthusiasm, motivation and a commitment to quality
Working Conditions / Demands
The role regularly requires the ability to effectively communicate. The role frequently requires the ability to move about the work environment and to position oneself to operate laboratory equipment effectively. The role requires the ability to move objects weighing up to 25 pounds and will occasionally work near moving mechanical parts. The person in this role must be able to perform the essential functions with or without an accommodation.