Job posting number: #7070807
Posted: October 8, 2020
Application Deadline: Open Until Filled
Job DescriptionA Postdoctoral position is available in the Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, United States. This position reports to Dr. Linghua Wang in Genomic Medicine Department.
We seek a talented and highly motivated Postdoctoral Fellow to work on bladder cancer immunogenomic profiling projects. Our primary research focus areas are: to apply innovative immunogenomics and bioinformatics approaches to better understand cell biology, tumor immune evasion and evolution, resistance mechanisms to cancer immunotherapy, by deep profiling of the cellular & functional heterogeneity of tumor cells and the diverse cell populations within the tumor immune microenviroment (TIME), the lineage plasticity and evolutionary dynamics of tumor cells and tumor-immune interactions.
The Postdoctoral Fellow will gain mechanistic understanding of tumor cell heterogeneity and immune resistance. Learn skills for immunogenomics and single cell sequencing data analysis, and cancer-specific bioinformatics. Learn study design, data analysis, interpretation, presentation, and manuscript writing. The Postdoctoral Fellow will carry out integrative analysis of the bulk and single cell sequencing (RNA/TCR/BCR/ATAC-seq), and immunogenomic datasets generated on clinical specimens from patients and animal models, to comprehensively characterize the tumor ecosystem and identify predictive/prognostic signatures/biomarkers and potential targets that could be harnessed to design rational therapeutic interventions. The Postdoctoral Fellow will have great opportunities to collaborate with diverse groups of physician scientists, laboratory scientists and computational biologists at MD Anderson Cancer Center and will be co-mentored by Dr. Linghua Wang, MD, PhD, PI of the Computational Biology Lab at the Department of Genomic Medicine and by Dr. Jianjun Gao, MD, PhD, Genitourinary Medical Oncology.
Individuals with a PhD degree in computational biology, bioinformatics, data science or a related field are encouraged to apply. A strong computational background, proficiency in R and at least one additional scripting language (e.g. Python, Perl) and knowledge in biostatistics are required. Experience working with single cell sequencing data analysis and high-performance computing environment (Unix/Linux) is highly preferred. A good understanding of cancer biology, immunology, cell biology, and molecular biology is also preferred. Proven track record of publications, excellent spoken and written communication skills are required.
Interested applicants should send a Cover Letter specifying past research experience/skills/accomplishments, a Curriculum Vitae and the contact information of three (3) Referees to Dr. Wang (Lwang22@mdanderson.org) and Dr. Gao (JGao1@mdanderson.org) with the subject line entitled “Postdoctoral Fellow - Application – Applicant’s Name”.
Consideration of applications will begin immediately and continue until the position is filled.
Stipend: Stipend support will follow the NIH Kirschstein-NRSA stipend levels level for the appropriate PGY.
It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law.
Diversity and inclusion at MD Anderson are not just important; they are essential. We take an expansive view of diversity, considering differences in race, ethnicity, sexual orientation, gender and religious beliefs, as well as communication styles, thought, skill and ambition. We constantly examine our culture to create an inclusive working environment that effectively attracts, retains, develops and utilizes the skills and talents of all employees. Our Diversity Council develops strategies to attract and retain superior talent and enhance workforce diversity and inclusion. We also offer multiple diversity training programs to our employees.